Hexyl 450

HEXYL 450 BY KALPA PHARMACEUTICALS

Injectable Oily Solution

DRUG COMPOSITION

1 mL of solution contains:
- active substances: 450 mg/mL
testosterone acetate 30 mg
testosterone propionate 73 mg
testosterone phenylpropionate 73 mg;
testosterone cypionate 125 mg;
testosterone decanoate 147 mg;
- auxiliary substances: benzyl alcohol, peach or peanut oil.

DRUG DESCRIPTION

Transparent oily solution, light yellow to yellow in color, with a characteristic odor.

Hexyl 450 is a composite testosterone product (mix) containing a calibrated mixture of short and long-acting esters, which provides the most even and prolonged action of the steroid (up to 2-3 weeks).

PHARMACEUTICAL FORM

Injectable oily solution.

PHARMACEUTICAL GROUP AND ATC CODE

Androgen; anabolic steroid; androgen ester; G03B A03.

PHARMACOLOGICAL PROPERTIES

Pharmacodynamics
Hexyl is composed of five testosterone esters (acetate, propionate, phenylpropionate, cypionate and decanoate). Testosterone is the primary androgen hormone synthesized and released by the testicles. It is responsible for the growth and development of male sexual organs and secondary sexual characteristics (maturation of the prostate, seminal vesicles, penis and scrotum), male hair distribution (face, pubis, chest), laryngeal development, body muscles and fat distribution. Retains nitrogen, sodium, potassium and phosphorus, increases anabolism and reduces protein catabolism. Premature increase in plasma of testosterone concentration in the prepubertal period causes the epiphyses to close and the growth to stop. Stimulates the production of erythropoietin and erythrocytes. Through a feedback mechanism, it inhibits the secretion of pituitary luteinizing and folliculostimulating hormones and causes the suppression of spermatogenesis.

In women it inhibits pituitary gonadrophic function, ovarian function, mammary glands, endometrial atrophy. Due to its antagonistic action against estrogen, it is used in the treatment of uterine fibroids, endometriosis, breast cancer. Manifests beneficial action in the climacteric period.

The effect of Hexyl 450 cycle for an athlete is a powerful anabolic, androgenic, even anti-catabolic. Throughout the cycle, this mix effectively contributes to building muscle mass and prevents its destruction, which explains its popularity. However, it's action is not limited to this: endurance and working capacity also develop, potential strength increases, fatigue decreases, the function of joints, ligaments and bones is strengthened and improved, the appetite and libido are strengthened. Testosterone has a wide spectrum of action, due to which it is relevant for almost any physical sports, including bodybuilding.

Pharmacokinetics
The testosterone esters in this preparation have different absorption and elimination rates, which ensures a fast and prolonged effect (up to 4 weeks) after a single administration: testosterone propionate and acetate acts for the first 24 hours. Testosterone phenylpropionate and cypionate begin to act over 24 hours after administration and last up to 2 weeks. Testosterone decanoate is the slowest after the onset of action, but with the longest duration. In the blood, about 98% of testosterone binds to a specific fraction of globulins, which binds testosterone and estradiol. Biotransformation occurs in the liver to various 17-ketosteroids, which after conjugation with glucuronic or sulfuric acid are excreted in the urine (approximately 90%). Approximately 6% of the absorbed preparation is excreted in the faeces in free form.

PROFILE

Half life: 7-8 days
Routes of administration: intramuscular injection
Dosage forms: (Men): 450 mg / 7 days; (Women): Not Recommended
Acne: yes
Water retention: yes (high)
High blood pressure: yes
Hepatotoxicity: no
Aromatase: yes (high, 100% of testosterone)
Progestogen activity: low
DHT (dehydrotestosterone) conversion: no
Decreased HPTA function (own testosterone production): yes (weak)
Anabolic activity: 100%
Androgenic activity: 100%
Detection time: 3 months after the last injection.

THERAPEUTICAL INDICATIONS

In men - androgenic deficiency after castration, eunucoidism, hypopituitarism, hormonal impotence, symptoms of male climax (decreased libido and physical and intellectual activity), some forms of infertility with impaired spermatogenesis, osteoporosis caused by insufficiency and; in women - hyperestrogenemia, uterine fibroids; endometriosis; breast cancer; osteoporosis.

Hexyl 450 is characterized by powerful anabolic and androgenic properties, which is why it is recommended exclusively for men for sports purposes. For women, the threat is androgenic side effect (virilization), expressed by symptoms of coarsening of the voice, increased aggression, and others.

DOSES AND METHOD OF ADMINISTRATION

Deep intramuscular. Hexyl dosage recommended for athletes 450 mg per week on average. Because this drug is long-acting and high dosed, intensive injection is not required, however, for a smooth background of action, rotate the injection site in order to avoid soreness and inflamation.

SIDE EFFECTS

Probable side effects: aggression, sweating, acne, suppression of testosterone production, water retention, gynecomastia and some others, due to increased androgenic or estrogenic activity. This steroid is highly aromattized, so in a heavy cycle there may be a need for taking an antiestrogen, such as Anastrozole.

CONTRAINDICATIONS

Individual hypersensitivity to the drug, prostate or breast cancer; prostate hyperplasia with symptoms of urinary disorders; nephrosis or nephrotic phase of nephritis, edema; hypercalcemia; liver function disorders; diabetes; heart or coronary insufficiency, a history of myocardial infarction, atherosclerosis in elderly men; pregnancy, lactation.

OVERDOSE

In acute overdose the toxicity of testosterone is quite low. In chronic overdose it is possible to develop priapism. In this case it is necessary to stop the administration of this drug, and after the disappearance of symptoms - to resume treatment in lower doses.

WARNINGS AND SPECIAL PRECAUTIONS FOR USE

In case of androgen-dependent side effects it is necessary to stop the administration of this drug. After the disappearance of the side effects, resume treatment in lower doses.

Patients with latent or overt heart failure, renal impairment, hypertension, epilepsy or migraine (or a history of these conditions) will be under constant supervision, as androgens may in some cases cause sodium and water retention. Liver function will be monitored during long-term treatment. In patients with breast cancer, hypernephroma, lung cancer with bone metastases, the level of calcium in the blood and urine will be controlled. In adolescents in the prepubertal period, androgens should be administered with caution to avoid stopping growth and premature puberty.

INTERACTIONS WITH OTHER DRUGS

Increases the effectiveness of anticoagulants and antidiabetics (dose adjustment is required), inhibits the elimination of cyclosporine. Inducers of liver enzymes (barbiturates, rifampicin, carbamazepine, phenylbutazone, phenytoin) reduce the effect of testosterone.

Due to the specificity of the effect, Hexyl 450 is used mainly in bulking cycles. It is a powerful enough anabolic steroid to be used in solo, but for maximum progress it is combined with other effective drugs: Nandroxyl, Turanaxyl, Dianoxyl, Boldaxyl, Primoxyl, Oxandroxyl and others, depending on your goals, sensitivity and tolerance of the body.

Here are some stack examples:

With Dianoxyl and Nandroxyl lasting up to 8-10 weeks. This is a powerful bulking stack, recommended mainly for experienced athletes. Average doses: 450 mg of testosterone and 400 mg of nandrolone per week (from the first to the last week), within 30-50 mg of methandienone per day (up to 6-8 weeks).

With Stanoxyl Depot lasting up to 6-8 weeks. This is a working cycle to increase potential strength, recommended by experienced athletes. Dosages of substances: an average of 450 mg of testosterone per week and as part of 30-50 mg of stanozolol per day. Stanozolol is either water or oil based.

Upon cycle completion, it is necessarily post-cycle therapy (PCT). The mix, although it is characterized by the predominant useful side effect, is able to greatly affect the synthesis of testosterone, to restore your natural testosterone production, use Nolvaxyl or Clomixyl.

PRESENTATION, PACKAGING

Injectable oily solution 450 mg / 1 mL in 10 mL vials.

STORAGE

Store in a dry place and away from light at 15-25 ° C. Keep out of the reach and sight of children.

LEGAL STATUS

It is issued with prescription.

DATE OF LAST TEXT CHECKS

May 2020

NAME AND ADDRESS OF THE MANUFACTURER

Kalpa Pharmaceuticals LTD.
India
www.kalpapharmaceuticals.com

EXTERNAL LINKS

Testosterone >> Wikipedia

Hexyl 450 Reviews >> GrowXXL

Kalpa Pharmaceuticals Reviews >> GrowXXL

Buy Testosterone Online USA >> Top Suppliers

Sustanon for Sale >> Top Suppliers