Enantat 400

ENANTAT 400 BY DRAGON PHARMA

Injectable Oily Solution

DRUG COMPOSITION

1 mL of solution contains:
- active substance: testosterone enanthate 400 mg;
- auxiliary substances: benzyl alcohol, peach or peanut oil.

LAB TEST REPORT

DRUG DESCRIPTION

Transparent oily solution, light yellow to yellow in color, with a characteristic odor.

Enantat 400 is the strongest steroid with anabolic and androgenic activity. At the basis of the drug is the active substance Testosterone Enanthate.

Enantat 400 is often used in sports activities. The drug is effective in bodybuilding, in triathlon, weightlifting and other physical disciplines. The main task of the drug is to build muscle mass, as well as the growth of strength indicators. Also Enantat 400 has other positive effects - muscle pumping, improved joint function and other important effects for an athlete.

A significant advantage, if you buy Enantat 400, is that it has a long time acting in the body. Depending on the hormonal background and body's metabolism, this steroid is active for 2-3 weeks. This advantage of the drug can eliminate the need for continuous injection.

PHARMACEUTICAL FORM

Injectable oily solution.

PHARMACEUTICAL GROUP AND ATC CODE

Androgen; anabolic steroid; androgen ester; G03B A03.

PHARMACOLOGICAL PROPERTIES

Pharmacodynamics
Testosterone Enanthate is an ester of testosterone. Testosterone is the primary androgen hormone synthesized and released by the testicles. It is responsible for the growth and development of male sexual organs and secondary sexual characteristics (maturation of the prostate, seminal vesicles, penis and scrotum), male hair distribution (face, pubis, chest), laryngeal development, body muscles and fat distribution. Retains nitrogen, sodium, potassium and phosphorus, increases anabolism and reduces protein catabolism. Premature increase in testosterone plasma levels in the prepubertal period causes the epiphyses to close and the growth to stop. Stimulates the production of erythropoietin and erythrocytes. Through the feedback mechanism it inhibits the secretion of pituitary luteinizing and folliculostimulating hormones and causes the suppression of spermatogenesis.

In women it inhibits pituitary gonadrophic function, ovarian function, mammary glands, endometrial atrophy. Due to its antagonistic action against estrogen, it is used in the treatment of uterine fibroids, endometriosis, breast cancer. Manifests beneficial action in the climacteric period.

Pharmacokinetics
Testosterone enanthate is absorbed slowly. Maximum plasma concentration is reached over 72 hours after intramuscular administration. Duration of action - 2-4 weeks. In the blood, about 98% of testosterone binds to a specific fraction of globulins, which binds testosterone and estradiol.

Biotransformation occurs in the liver to various 17-ketosteroids, which after conjugation with glucuronic or sulfuric acid are excreted in the urine (approximately 90%). Approximately 6% of the absorbed preparation is excreted in the faeces in free form.

PROFILE

Half life: 15-16 days
Routes ofadministration: intramuscular injection
Dosage forms: (Men): 400-800 mg / 7 days; (Women): Not Recommended
Acne: yes
Water retention: yes (high)
High blood pressure: yes
Hepatotoxicity: no
Aromatase: yes (high, 100% of testosterone)
Progestogen activity: low
DHT (dehydrotestosterone) conversion: no
Decreased HPTA function (own testosterone production): yes (weak)
Anabolic activity: 100%
Androgenic activity: 100%
Detection time: 3 months after the last injection.

THERAPEUTICAL INDICATIONS

In men - hormone replacement therapy for testosterone deficiency disorders:
- retention of sexual maturation;
- eunucoidism, non-development of the genitals;
- impotence of hormonal origin;
- hypopituitarism;
- male climax symptoms (decreased libido and physical and intellectual activity);
- post-castration syndrome (androgenic deficiency after castration);
- osteoporosis caused by androgenic insufficiency.

For women:
- hyperestrogenemia, functional hemorrhages;
- uterine fibroids;
- endometriosis;
- menopause (in combination with estrogen);
- breast cancer;
- osteoporosis.

DOSES AND METHOD OF ADMINISTRATION

Deep intramuscular. The dose is determined individually depending on the disease, sex, age, clinical efficacy. Adults are usually given 50-200 mg intramuscularly once every 2-4 weeks. It is not recommended to exceed the dose of 400 mg per month. The duration of treatment is determined individually.

In hypogonadism in men like eunucoidism, the recommended doses are 50-400 mg every 2-4 weeks.

In case of retention of sexual maturation, 50-200 mg are administered every 2-4 weeks for 4-6 months.

In inoperable breast cancer in women: 200-400 mg every 2-4 weeks.

For bodybuilding purposes, average dosage: men 400-800 mg per week, women not recommended. The duration of a cycle varies between 8 and 10 weeks.

The drug is not administered intravenously!

SIDE EFFECTS

- Priapism and other symptoms of sexual hyperstimulation (frequent erection);
- in adolescents of prepubertal age - accelerating sexual development; increase in the frequency of erections, increase in the sexual organ in size, premature closure of the epiphyses;
- impaired spermatogenesis and disorders of sperm maturation, oligospermia and reduced ejaculate volume;
- prostate abnormalities;
- in women - bleeding from the genitals, increased libido; symptoms of virilization are possible with prolonged administration;
- hirsutism, gynecomastia;
- seborrhea, acne, oily skin, hair loss;
- sodium and water retention, edema;
- symptoms of hypercalcaemia;
- thrombophlebitis;
- nausea, cholestatic jaundice, increased levels of liver transaminases (normalizes when treatment is stopped);
- headache, depression, aggression, anxiety, sleep disorders, paresthesias.

Pain, pruritus and hyperemia at the injection site are possible.

It is important to know that the use of Enantat 400 in sports need to be careful, since this steroid has a number of side effects. There is a share of the likelihood that some androgenic side effects may appear on cycle, such as: weight gain, acne rash, the intensity of hair growth on the face and body.

It is known that Enantat 400 is an aromatized drug, which means the occurrence of anxiety and estrogenic side effects. Perhaps an athlete will grow a fat layer, gynecomastia will appear or the water in the body will be delayed. In order to avoid such effects, athletes often use anti-estrogenic drugs. It can be Clomid/Clomixyl/Clomed or Tamoximed/Nolvadex/Nolvaxyl.

It is worth noting that this steroid should not be used by women, since Enantat 400 provides a very strong androgenic effect on the body. When this steroid is used by woman, it can become a trigger for the birth of masculinization, where it is possible to develop male sexual characteristics.

CONTRAINDICATIONS

Individual hypersensitivity to the drug, prostate or breast cancer; prostate hyperplasia with symptoms of urinary disorders; nephrosis or nephrotic phase of nephritis, edema; hypercalcemia; liver function disorders; diabetes; heart or coronary insufficiency, a history of myocardial infarction, atherosclerosis in elderly men; pregnancy, lactation.

OVERDOSE

In acute overdose, testosterone toxicity is quite low.

In chronic overdose it is possible to develop priapism. In this case it is necessary to stop the administration of the drug, and after the disappearance of symptoms - to resume treatment in lower doses.

WARNINGS AND SPECIAL PRECAUTIONS FOR USE

In case of androgen-dependent side effects it is necessary to stop the administration of the drug. After the disappearance of the side effects, resume treatment in lower doses.

Patients with latent or overt heart failure, renal impairment, hypertension, epilepsy or migraine (or a history of these conditions) will be under constant supervision, as androgens may in some cases cause sodium and water retention. Liver function will be monitored during long-term treatment. In patients with breast cancer, hypernephroma, lung cancer with bone metastases, the level of calcium in the blood and urine will be controlled. In adolescents in the prepubertal period, androgens should be administered with caution to avoid stopping growth and premature puberty.

INTERACTIONS WITH OTHER DRUGS

Increases the effectiveness of anticoagulants and antidiabetics (dose adjustment is required), inhibits the elimination of cyclosporine. Inducers of liver enzymes (barbiturates, rifampicin, carbamazepine, phenylbutazone, phenytoin) reduce the effect of testosterone.

PRESENTATION, PACKAGING

Injectable oily solution 400 mg / 1 mL in 10 mL vials.

STORAGE

As for the storage of Enantat 400, it should be stored in places protected from sunlight at an average room temperature. Also, in precautions, make sure that the drug is in an unreachable place from children.

Store in a dry place and away from light at 15-25 ° C. Keep out of the reach and sight of children.

LEGAL STATUS

It is issued with prescription.

DATE OF LAST TEXT CHECKS

June 2020

NAME AND ADDRESS OF THE MANUFACTURER

Dragon Pharma.
Europe
www.dragon-pharma.com

EXTERNAL LINKS

Enantat 400 Lab Test Results >> JPG

Testosterone Enanthate >> Wikipedia

Enantat 400 Reviews >> GrowXXL

Dragon Pharma Reviews >> GrowXXL

Dragon Pharma Sources >> Top Suppliers

Legit Testosterone Sources >> Top Suppliers